If you follow me on twitter or like my Facebook page then you’ve probably seen all the posts and tweets about that new mouse study that made it’s way in the LA Times and various other media outlets.
(If you don’t follow me, but like random misspelled thoughts on health and fitness, then you need to get on my face book page –> www.facebook.com/BradPilon  It’s kind of like my blog, only a little more distracted)
In this particular study mice who OR OR 

Original post by Brad Pilon

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pimg class=”alignright” title=”Pea Sprouts” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/peasprouts.jpg” alt=”peasprouts” width=”319″ height=”254″ /Since it seems to be popular with this crowd, and we#8217;re never running out of questionable foods, I figured I#8217;d take the time to put together another round of #8220;a title=”Is It Primal? – 8 More Foods Scrutinized ” href=”http://www.marksdailyapple.com/is-it-primal-8-foods-scrutinized/#axzz1vduwa16y”Is It Primal?/a#8221; I got most of these choices from the comment sections of previous posts, along with follow-up emails. As always, feel free to fill in the blanks after the post. I have a strong feeling this will become a recurring series of posts, and I#8217;m going to need plenty of material. Today, we#8217;re talking about seven foods: sprouts of all kinds and origins; agave nectar, nectar of the metabolic syndrome gods; soy lecithin; coconut aminos, what hipsters have moved onto from tamari; tapioca, gummy starch; animal skin, food of the gods; and Quorn, #8220;food.#8221;/p
pLet#8217;s go:/p
pspan id=”more-29360″/span/p
h3Sprouts/h3
pSprouts are a bit […]

Original post by Mark Sisson

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pimg class=”alignright” title=”Pea Sprouts” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/peasprouts.jpg” alt=”peasprouts” width=”319″ height=”254″ /Since it seems to be popular with this crowd, and we#8217;re never running out of questionable foods, I figured I#8217;d take the time to put together another round of #8220;a title=”Is It Primal? – 8 More Foods Scrutinized ” href=”http://www.marksdailyapple.com/is-it-primal-8-foods-scrutinized/#axzz1vduwa16y”Is It Primal?/a#8221; I got most of these choices from the comment sections of previous posts, along with follow-up emails. As always, feel free to fill in the blanks after the post. I have a strong feeling this will become a recurring series of posts, and I#8217;m going to need plenty of material. Today, we#8217;re talking about seven foods: sprouts of all kinds and origins; agave nectar, nectar of the metabolic syndrome gods; soy lecithin; coconut aminos, what hipsters have moved onto from tamari; tapioca, gummy starch; animal skin, food of the gods; and Quorn, #8220;food.#8221;/p
pLet#8217;s go:/p
pspan id=”more-29360″/span/p
h3Sprouts/h3
pSprouts are a bit […]

Original post by Mark Sisson

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pimg class=”alignright” title=”No thank you.” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/sharingbread.jpg” alt=”sharingbread” width=”287″ height=”244″ /As I#8217;m sure you#8217;ve seen, eyes raise and questions arise when you order a burger wrapped in lettuce or discard a #8220;wrap#8221; and eat the contents. And then, when you answer with #8221;Oh, I don#8217;t eat grains,#8221; minds boggle and mouths gape as they stumble to grasp the notion of someone who doesn#8217;t eat bread or pasta. Eventually, though, they fire off responses, challenges, questions, and proclamations. This isn#8217;t right, this isn#8217;t possible, this doesn#8217;t agree with their idea of how people should eat. It just isn#8217;t normal. emYou#8217;re/em not normal, and you should be ashamed of yourself for introducing a new a title=”A Metabolic Paradigm Shift, or Why Fat is the Preferred Fuel for Human Metabolism” href=”http://www.marksdailyapple.com/a-metabolic-paradigm-shift-fat-carbs-human-body-metabolism/”paradigm/a. But not all are personally offended by your decision. Some are honestly curious and flabbergasted. Some just want to know emwhy/em someone would give up grains and emhow/em they […]

Original post by Mark Sisson

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Kyle gets really excited about not eating!For most of my athletic “career” I’ve been adding more features: more movements, more good foods, more cutting edge methods.  It never occurred to me that less could be better, especially with my food intake (I’ve always been skinny and trying to add weight). But recently on Primal Personality, Mark Sisson’s site (Marksdailyapple.com), I came across a series on intermittent fasting that brought up some pretty persuasive arguments for the benefits of occasional fasting. Further research corroborated the information on the Daily Apple: that going without grub for extended periods of time can have serious advantages for weight loss, lean muscle retention, longevity, brain health, disease prevention and improved determination and confidence.Coming from a guy who ranks eating among his top three favorite things to do close behind baby-making and sleep, fasting doesn’t exactly have strong appeal.  But in the face of the facts, I’ll be observing a weekly fast day for a month and reporting the results to you.One of the primary affects of fasting is pretty obvious: weight loss.  Not only does fasting restrict calorie intake, but it also encourages the secretion of growth hormone and decreases insulin levels.  GH is a primary fat burning hormone and insulin is what stores fat in our bodies (less of it allows more fat to be burned)[i].  All of these factors working together make for a mean weight loss punch, while keeping that lean muscle mass you worked so hard to get at Rugged Crossfit.With some of the junk we put in our bodies today, it’s not crazy that some days we feel like trash.

More here:

GONE GHANDI: INTERMITTENT FASTING | DigBoston

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pimg class=”alignright” title=”Cold Water Plunge” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/coldwaterplunge3-1.png” alt=”coldwaterplunge3 1″ width=”287″ height=”267″ /emBefore we get to the topics du jour I#8217;d like to express my appreciation to everyone that participated in a title=”Dear Readers: What Do You Want?” href=”http://www.marksdailyapple.com/dear-readers-what-do-you-want-2/”last week#8217;s #8220;Dear Readers#8221; comment board/a. As I said, Mark#8217;s Daily Apple, my books, and what I do is constantly informed by your thoughts and ideas. In other words, I couldn#8217;t do this without you, so thank you for your feedback./em/p
pemMy team and OR OR 

Original post by Mark Sisson

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It’s what Charles Mobbs, a neuroscientist from the Mount Sinai School of Medicine, calls the “metabolic mystery.”  Since the early 1930s, research studies have consistently demonstrated that too many nutritional resources, resulting in conditions like obesity and diabetes, can be toxic to the brain.  In contrast, more restrictive diets result in a complicated (and counterintuitive) cascade of protective effects, preventing aging-related diseases and ultimately prolonging life.  Today, neuroscientists are learning that the old adage, “you are what you eat,” might need to be updated to “you are how you eat.”  And the new work from the National Institutes of Aging suggests that fasting may help promote optimal brain health in aging adults.Eating: Less is more?Several studies have demonstrated that regular exercise helps protect the brain from age-related decline.  But in a recent essay published in the March 2012 issue of Nature Reviews Neuroscience, Mark Mattson, a neuroscientist at the National Institute of Aging, argues that diet is just as important.  Specifically, he cites results demonstrating that intermittent fasting—one day on food, the next day off of it—can also protect the brain.  So why might abstaining from food every 24 hours be such a brain benefit? “Fasting is a challenge to the nervous system, to the energy regulating systems,” says Mattson.  “And what we’re thinking, from the standpoint of evolution, is that animals living in the wild, including our ancestors, often had to go extended time periods without food.  If you haven’t had food for a while, your mind becomes more active—it has to become very active, to help you figure out how to find food.”That activity manifests itself in neuroplasticity; in mouse models, Mattson and colleagues have shown that intermittent fasting helps protect the brain from both oxidative stress and direct injury.  Those protective effects result in the upregulation of brain-derived neurotrophic factor (BDNF) as well as anti-oxidants, DNA-repair enzymes, and other gene products that help promote plasticity and survival of neurons over time.“It makes evolutionary sense that caloric availability would have an impact, not just on brain regions involved in metabolism, such as the hypothalamus, but also on brain regions involved in learning, such as the hippocampus,” says Alexis Stranahan, a professor at Georgia Health Sciences University and Mattson’s co-author on the Nature Reviews Neuroscience essay.  “Your mind needs to be sharp if you are looking for food.  At the other end of the spectrum, it also makes sense that an overabundance of food would dull the senses, making it harder to form associations.”In the past, some studies suggested that caloric restriction promoted good health—and researchers have seen improved outcomes in animal models of Alzheimer’s disease, Parkinson’s disease, stroke and Huntington’s disease by simply reducing the number of calories an animal eats each day by a significant percentage.  But Mattson argues that, when it comes to the brain, fasting may be more effective.  “We find that the intermittent fasting increases neurogenesis while limited daily reduction in calories has very little effect,” he says.  “BDNF levels are increased in response to both exercise and intermittent energy restriction.”Fasting and human trialsTo date, intermittent fasting has been tested in two human trials.  The first was conducted by James Johnson, a plastic surgeon and professor at Louisiana State University, who was inspired by Mattson’s work.  He was interested in seeing if caloric restriction might help reduce inflammation and breathing issues in people with severe asthma.“I had a patient who had asthma who used three inhalers plus some oral medication every day,” he says.  “After three weeks of alternate-day fasting, she was down to using the inhalers once a day.  And after six weeks, she stopped using the inhalers at all.  Her asthma symptoms had essentially gone away.  It was astonishing.”Johnson partnered with Mattson and other local scientists to do a small clinical trial.  They recruited 12 overweight people with asthma to take part in an alternate-day fasting-like regimen.  Participants alternated eating whatever they wanted on “on” days and consuming shakes that limited caloric intake to 500-600 calories on “off” days, for two months. “It was a small trial but participants lost weight.  They said they felt good.  And their asthma symptoms improved,” says Mattson.  Measurements of airway resistance improved and the researchers found many markers of inflammation and oxidative stress diminished over the first few weeks.  Johnson marked it enough of a success to write a book about the regimen, called “The Alternative Day Diet.” A second clinical trial, led by the University of Manchester’s Michelle Harvie, divided a group of about 100 overweight women with a high risk of breast cancer into three diet groups:  average diet, a diet that restricted calories overall by 15 percent and intermittent fasting (with “off” days permitting 600 calories).  The results have not been published yet but, once again, Mattson says participants in the fasting group lost weight and improved their insulin sensitivity. Moving forwardBetween the replicated work in animal models and the success of the two small clinical trials, Mattson now has his sights set on the human brain.  He and his colleagues are planning to do a study looking at people who are at risk for age-related cognitive decline.  He is optimistic that the results will mimic those seen in the smaller trials, demonstrating solid protective effects in the cortex.  He and his colleagues also plan to contrast intermittent fasting with exercise in animal models. Mobbs, however, cautions that there’s no reason for everyone to start fasting just yet.  He maintains that there is still quite a bit we don’t know about caloric intake and the brain. “That’s why I call it the ‘metabolic mystery.’  And certainly we know that diseases like anorexia are very toxic to the body and the brain.  We don’t know when or how these processes go from being healthy to unhealthy yet,” he says.  “So your best bet for a healthy brain and a healthy body is still to listen to your doctor and use common sense:  follow a reasonable caloric intake, exercise, and avoid obesity.”

Excerpt from:  

The Brain's Metabolic Mysteries – Dana Foundation

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pimg class=”alignright” title=”Chicken Liver Pate” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/pate2ways.jpg” alt=”pate2ways” width=”320″ height=”212″ /If you’ve only ever had a title=”Organ Meats” href=”http://www.marksdailyapple.com/organ-meats/#axzz1v33TRN6c”chicken livers/a fried with onions or chopped up with hardboiled eggs, then it’s time to experience liver in a more decadent way. Not that Grandma’s chopped liver doesn’t hit the spot sometimes, but the smooth, whipped texture and buttery flavor of emChicken Liver Pâté/em is really something special./p
pThe secret to silky, smooth pâté is twofold. First, simmering the liver in liquid instead of browning it prevents the liver from drying out while cooking. The second “secret” – and actually, this shouldn’t be OR OR 

Original post by Worker Bee

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pIt’s Friday, everyone! And that means another a title=”Success Stories” href=”http://www.marksdailyapple.com/category/success-story-summaries/”Primal Blueprint Real Life Story/a from a Mark#8217;s Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’s Daily Apple community please contact me a title=”Contact Me!” href=”http://www.marksdailyapple.com/the-book/share-success-story/” target=”_self”here/a. I’ll continue to publish these each Friday as long as they keep coming in. Thank you for reading!/p
/div
pimg class=”alignright” title=”Primal Blueprint Real Life Story” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA2009/real_life_stories_stories-1-2.jpg” alt=”real OR OR 

Original post by Mark Sisson

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pimg class=”alignright” title=”Peanut Butter” src=”http://i247.photobucket.com/albums/gg158/MDA2008/MDA%202011/peanutbutter.jpg” alt=”peanutbutter” width=”280″ height=”287″ /Man, you guys really love your peanut butter./p
pI get at least one email a week from a devoted reader of the blog who just can#8217;t shake the desire (that feels like a need) to eat peanut butter on a regular basis. They#8217;re on board with everything else. They#8217;ve ditched a title=”Why Grains Are Unhealthy” href=”http://www.marksdailyapple.com/why-grains-are-unhealthy/”grains/a and vegetable oils. They#8217;re walking more and getting better sleep. They#8217;re getting sun and a title=”How to Eat More Vegetables” href=”http://www.marksdailyapple.com/how-to-eat-more-vegetables/#axzz1uzX6kh3G”eating more vegetables/a than ever before. They#8217;ve switched to a title=”The Differences Between Grass-Fed Beef and Grain-Fed Beef OR OR 

Original post by Mark Sisson

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