This post was originally published on this site

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There’s something special about Sunday habits. While the morning and evening rituals that make up the rest of the week keep our kitchen lives sane and steady, it’s what we do on Sunday that sets the tone. Good Sunday habits should both close off the week prior, and send you prepped and cheered into the week ahead.

While there are many ways to spend a Sunday in the kitchen, here are five small things we like to do before the night is over.

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etiquette-1-nervouswoman This post was originally published on this site

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Walking into a new gym or fitness facility can feel a little (or a lot!) intimidating for some of us. Looking around on that first visit, you see members who appear to know the gym inside and out, who are comfortable and not the least bit self-conscious.

 

And then there’s you. Walking by with your stuff, looking around, taking it all in. As the new member, you might sometimes feel lost (I mean, where is the darn locker room?!), and you might get the notion that everyone else is staring and judging. Pssst… they’re not!

 

etiquette-1-nervouswoman

 

At Girls Gone Strong most of us have been new to a gym more than once. Each first time can be intimidating or exciting, or a little bit of both. Gyms, much like people, are all unique to some degree. Each one has its own culture, type of member, and overall vibe.

 

Today we want to share some advice to help you feel like you’re walking into the gym like a boss, whether it’s your first first time, or your tenth first time.

 

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First things first: Do a little “recon”

 

The very first step you can take toward feeling confident at your new gym is to ask for a tour so you can get to know the lay of the land and get a feel for the culture and vibe of the place.

 

Ask questions, don’t hold back. Find out where the locker room. Ask about the type of equipment they have (kettlebells, suspension training straps or rings, bands, barbells, platforms, chains, etc.). Some gyms restrict the use of certain equipment for personal training clients only, so ask whether using them all is included in your membership. Ask if the gym offers classes, personal training or any other services.

 

After you’ve got the basics covered, it’s good to know some standard, and often unwritten but generally understood, rules and common courtesies that generate good gym karma and can keep you and your fellow gym members safe and happy.

 

In the Locker Room

 

It’s a good idea to wear sandals or slippers when changing and showering. No matter how well-kept and clean the area looks, locker rooms and showers can be a warm, moist petri dish where microscopic yuckies can easily multiply.

 

Let’s be crystal clear: at Girls Gone Strong we unequivocally encourage body confidence. However, unless it’s culturally appropriate (both abroad in foreign gyms, or at home in a particular gym), consider limiting the amount of time you spend hanging around nude in the locker room—especially if seems like you’re the only one doing that. Not only could it make others uncomfortable if it’s just not that kind of culture, it’s too easy to pick up extra germs and microbes. Our skin is an important barrier, but it also absorbs a lot of what’s in our environment.

 

Take only as much space as you need on a bench or counter with your stuff, as a consideration to other members who need to use that space or the space around you. Some people may speak up, but often, they don’t. If all the contents of your gym bag are on the bench, or all your make-up and toiletries are spread across the whole counter, it may be a huge inconvenience to someone else who’s also trying to get ready and head out to work on time. Don’t hesitate to politely ask for some space if you’re the one needing a little more room.

 

If they’re available at your gym, and you tend to have a lot of stuff with you in the locker room, it might be worth it to spend a little extra and rent a long-term use locker. You can use it to store workout clothes, shoes, shampoo, and shower essentials, rather than lugging it back and forth every time. If you’d rather not leave things at the gym, invest in a combination lock and a good gym bag to safely store your stuff in a day-use locker.

 

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If you use the towels provided by the gym, make sure you put them in the “used towel” laundry bin after you use them.

 

Understandably, the gym can be a smelly place—nothing that a little spritz of something scenty can’t fix! However, be considerate when using fragrances and lotions. A sneezing fit can really put a damper on someone’s workout.

 

What to Wear

 

Some gyms have a dress code, and some don’t. Some enforce it, and some don’t. When in doubt, check your gym’s policies on shoes and clothing, or at the very least, use common sense by evaluating your environment and the gym’s culture. It seems obvious that you shouldn’t wear jeans or khakis with big pockets that can not only be abrasive on the upholstery of benches and seats, but more importantly this type of clothing can pose safety risks by restricting your movements or getting caught on equipment.

 

Depending on the gym and the type of activities and equipment available, members might want to wear clothing that covers up more skin (rather than just shorts and a sports bra), to prevent the spread of skin infections.

 

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Most gyms also request that you wear shoes, though some will allow you to go barefoot or wear socks for warm ups and certain lifts. For example, some people prefer to wear Olympic weight lifting shoes, socks, or simply go barefoot while deadlifting. It’s a good idea to check if this is OK before you do it.

 

Where to Warm Up and Stretch

 

We always encourage that you perform a good warm-up before your workout. Find an area designated for warming up, stretching, foam rolling, etc. If your gym doesn’t have a designated space, be courteous to other members and find a low-traffic spot that’s clear of equipment and people and provides enough room to do your thing safely. Perhaps a hallway, the space behind or adjacent to cardio machines, or even outside if it’s a nice day and there’s a safe area where you won’t get hit by a car or be in someone’s way.

 

etiquette-4-womanstretching

 

In the Gym

 

“A place for everything and everything in its place,” as the saying goes. Isn’t it such a pain when you go look for a particular piece of equipment (for example, dumbbells or a cable attachment), and it’s not where you expect it to be? And it’s so confusing and inconvenient when you finally spot it across the room, unattended and aren’t sure if someone else is using it, or if they’re done and just left it there. And sure, some people joke that “it’s part of the workout” to carry it around or clean up after someone else, but come on. It’s no fun to unload a fully-loaded barbell someone else left behind in order to prepare it for your own workout.

 

Yeah, don’t be that person to someone else. The courteous thing to do (without exception) is to unload the bar and re-rack all weights and dumbbells. It’s also a great way to keep the area safe for yourself and other members. On the flip side, if you do need some help to unloading a bar, or want someone to clear their weights out of the way (and ideally back to their home on the rack) after they’re done with them, speak up and ask them.

 

Uhhh…what?!

 

If you don’t need a particular piece of equipment, make sure you don’t appear to be “hoarding” it and keeping other members from using it. Whether it’s dumbbells, a bench that’s just acting as a place to rest your jacket and water bottle, or the squat rack if you’re doing something that can be done outside of it.

 

Speaking of benches, if there is only one adjustable bench (a bench that can adjust from flat to incline) try not to use that bench to perform flat bench exercises if you notice other non-adjustable flat benches available. It’s not a huge deal, just a thoughtful courtesy for fellow members.

 

It can get annoying in a hurry (not to mention how potentially not safe it is) to have to repeatedly step around someone who’s using way more space than they actually need. As with your space in the locker room, be aware of the space and equipment you’re using in the gym, and spend only the necessary amount of time using it, particularly if you notice others waiting or trying to share the space. That’s not to say you should hurry and move along. You pay your membership dues like everyone else, so don’t let anyone make you feel like you need to rush through your workout.

 

By the way, it’s totally OK to politely ask someone to move or make some room for you if you see them “hoarding” a space or specific equipment in that way (like someone doing an hour’s worth of biceps curls in the squat rack while you’re hoping to set up for a good squat sesh some time this year). Most of the time these people aren’t doing that stuff on purpose, they just aren’t thinking about it or are unaware that someone is waiting on them to finish. Give them a little tap on the shoulder and ask.

 

Does your gym have platforms? These boxes are intended for deadlifting or Olympic weight lifting to allow force distribution from dropping loaded barbells. They’re often raised a couple of inches off the floor, or may be built-in and level with the gym floor. Typically there’s a wooden section between two rubber side sections. Not all gyms have them. If you’re looking to deadlift at a gym that doesn’t have platforms, be considerate and try your best to be gentle when dropping the bar, especially if that doesn’t seem to be common at this gym.

 

The “place for everything” rule also applies to cable machine attachments. You’ll usually find different cable equipment options at most gyms. As a courtesy to other members and for everyone’s safety, if you’re switching out cable attachments (like handles, bars, or ropes), be sure to return them to their rack or hook if there is one, instead of leaving them on the floor in front of the equipment.

 

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Cable equipment often has a lot of moving parts, and how to use it correctly isn’t always immediately obvious. If you don’t know how to use a particular type of equipment, your best bet is to ask, both to ensure you are performing the exercise safely and to prevent damaging the equipment due to misuse.

 

In addition to free weights and cables, there are two common types of weight machines: plate-loaded (like Hammer Strength) and machines with weight stacks with pins (referred to as selectorized machines). As with free weights, be courteous and re-rack the weights if you’re using a plate-loaded machine.

 

If your gym has them, use the disinfectant wipes or spray and towels to wipe down handles, mats, benches, or seats after you’ve used equipment, especially if you’re sweaty. Don’t be afraid to give something a wipe down before you use it, too.

 

If you’re taking a class, you’ll typically pick out your equipment (weights, mat, step and risers, etc.). Be sure to wipe it down and put it away after class. Let your instructor know if you have any injuries or special needs that might require modification of the workout. Don’t hesitate to stop, or speak up and ask for an alternative if something doesn’t feel right for your body.

 

Social Interaction

 

In general, it depends on the gym, the members, and even the time of day when people are there. Not everyone goes to the gym to socialize, and not everyone is outgoing, so don’t feel offended if you smile at someone or say hello and they barely acknowledge you (sometimes they have their tunes playing and didn’t even hear you!). As we often say, do you. If you are the kind of person who smiles and says hello, keep doing it. If you’re a little more reserved, that’s fine too.

 

Gotta get your workout done, but someone’s using something you want to use? At the gym, it’s understood that whoever’s using something essentially called dibs on it, and other members typically will wait their turn, ask to work in, or do something else. Give and take is the name of the game. Be polite, but don’t be afraid to ask for what you need. If someone’s using the equipment and space you need, and you’re crunched for time, ask to “work in” with them.

 

By alternating sets with another member (“I go, you go” style), you can maximize your use of time, rather than waiting. It’s always nice to extend this same courtesy if you notice someone waiting to use the equipment you’re using. Invite them to work in with you.

 

If you don’t have a workout partner and need someone to spot you, ask a trainer, or fellow gym member if you feel confident that they’ll be able to spot you. Look around and trust your gut before you ask anyone. If you’re not sure any of the people around you will be able to help, consider doing another exercise or using lighter weight. Always think about your safety.

 

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With just a quick scroll through Instagram it’s immediately obvious that a lot of us love to show that we’re rockin’ it (crushing it, killing it, and tearing it up) at the gym. We share for so many reasons: for accountability, to highlight a PR, to celebrate our strength, to motivate a friend. Whatever your reason, go for it! It’s fun to see what our fellow #GirlsGoneStrong are up to.

 

As you’re setting up a photo, be thoughtful about others who might be waiting for the equipment or who might not want to be in your photo (even in the blurry background). And while we’re on the subject of phones and social media, it’s best to keep the following to a minimum: texting, talking, scrolling through Facebook/Insta/Twitter, or posing for multiple selfies while others are waiting.

 

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Anything else? In general, just ask. If a trainer or a staff member isn’t available, chances are good that there are knowledgeable members who will be happy to help, though they may not be experts. If you have questions, and find some friendly and willing members, strike up a conversation and ask for some advice. However, if you need advice on more serious or sensitive matters, especially relating to an injury or pain, it may be best to ask a personal trainer who works at the gym (or your doctor, ideally).

 

There you have it—you can’t go wrong with these top gym etiquette tips. Did we miss something? We would love for you to add some of your own tips in the comments below.

 

 

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pa href=”http://cdn.marksdailyapple.com/images/downloads/mymosaic3.jpg” rel=”lightbox[55393]”img class=”alignright size-full wp-image-55418″ src=”http://cdn.marksdailyapple.com/wordpress/wp-content/uploads/2015/05/mymosaic3.jpg” alt=”” width=”320″ height=”320″ //aWe’re a href=”http://www.marksdailyapple.com/is-it-all-just-a-paleofantasy/”cavemen/women-wannabes/a, deluded health nuts, nonconformist cynics, shameless meatlovers, a href=”http://www.marksdailyapple.com/the-barefoot-backlash-are-the-naysayers-right-after-all/”barefoot/a rabble #8211; the list goes on and on. People who don’t know any better may assume a lot of things about us. We’ve probably all been in a href=”http://www.marksdailyapple.com/how-to-overcome-the-naysayers-in-your-life/”these situations/a by now, right?/p
pIf you asked random people on the street about their perceptions of Primal/paleo adherents, I’d venture to say that a lot of them would say we’re beefy single men in our 20s #8211; maybe 30s #8211; who spend our days in the gym. Kinda funny, since the majority of MDA readers (by about 10% anyway) are actually a href=”http://www.marksdailyapple.com/women-and-intermittent-fasting/”women/a. And last time I checked not all of us #8211; my “old” self included #8211; have seen 30 in a while. We’re not all Californians or even warm weather folk who spend our days a href=”http://www.marksdailyapple.com/a-primal-take-on-body-image/”shirtless/a and […]

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RHR-new-cover-lowres-200x200 This post was originally published on this site

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RHR-new-cover-lowres

Methylation is essential for the optimal function of almost all your body systems. It occurs probably billions of times every second. In doing so, it helps repair your DNA on a daily basis, it helps keep inflammation in check, it replenishes the compounds needed for detoxification, and it helps maintain a stable mood.

In this episode, we cover:

3:55  Amy’s background
7:40  What is methylation?
14:12  Physiological processes affected by methylation
23:53  Symptoms associated with poor methylation

[powerpress]

Steve Wright: Good morning, good afternoon, and good evening. You are listening to the Revolution Health Radio Show. I’m your host, Steve Wright, co-author at SCDlifestyle.com. This episode of the RHR Show is brought to you by 14Four.me. This website and this program is a 14-day healthy lifestyle reset program that Chris Kresser has put together to help you if you’re still struggling with, for instance, weight loss, maybe even weight gain, sleep issues, autoimmune conditions, digestive health. Basically if you’re having any health-related conditions and you’re still not where you want to be, optimizing your diet, your sleep, your movement, and your stress are really the foundational principles to getting these problems resolved, and what Chris has done is put together a 14-day step-by-step program that’s going to walk you through fitting all these new changes into your life, and as we all know, implementing healthy habits can be a real struggle, so it’s really good and really wise to work with somebody who has done this with hundreds and thousands of other people and using science-based principles and habit-based principles that can really make it easy for you to implement these things into your life and take your health up to the next level. So check out 14Four.me.

Now, with me is integrative medical practitioner, healthy skeptic, and New York Times bestselling author, Chris Kresser.

Chris Kresser: Hey, everybody. It’s Chris Kresser here. We’re going to do something a little bit different this week. I have Dr. Amy Nett with me. She is a staff physician at the California Center for Functional Medicine, our clinic, CCFM. And I decided to ask Amy to come on the show and discuss methylation. I know we did a show about this a while back, but since then we’ve received a lot of questions from people asking us to just simplify things a little bit. Amy and I have been seeing it a lot in the clinic. We’re treating it a lot now. We’re kind of in a deep dive in terms of researching it and working out what it means for us and our patients, so I thought it’d be a good idea to bring Amy on and talk a little bit more about it in simpler terms and then more practical terms, like how we test for methylation problems, what happens in the body when methylation isn’t working right, and of course, how we treat it. So, welcome, Amy. Good to have you on the show!

Dr. Amy Nett: Thanks so much, Chris, for having me on the podcast this week. I’m excited to be here and talk about methylation a little bit more because as you mentioned, it is something we’re seeing more and more in the clinic and really working on optimizing methylation in a lot of our patients and seeing some really good results. But as you mentioned, it’s also something that can feel like a pretty overwhelming topic, so I’m hopeful that today we can clarify it a little bit more and make it seem a little more approachable.

Chris Kresser: Great. Yeah, and I’m sure what will happen is after this we’ll get some more questions, and then we can do a follow on it. It’s a huge topic, and, of course, we could do several episodes on it, and maybe we will. But before we do that, before we jump in, for those of our listeners that aren’t familiar with you, haven’t read any of your guest posts on the blog and just aren’t familiar with your work, why don’t you tell us a little bit about your history, your background, and how you came to be a staff physician at CCFM?

Dr. Amy Nett: Yeah, of course. I initially did my undergraduate training at UC – Santa Barbara, where I earned a bachelor’s degree in pharmacology. And I really loved science and also working with people, so I decided to go to medical school, and I earned my medical degree from Georgetown University. And for a number of reasons, I fell into radiology, and radiology, for people who aren’t familiar with that, it’s really biomedical imaging, so it’s interpretation of MRI/CT/ultrasound imaging. I did my training in radiology at Stanford University, which is what brought me out to the Bay Area, and after completing the basic residency in radiology, I ended up doing specialty training in pediatric radiology also at Stanford University. And in doing the training in pediatric radiology, I saw a lot of kids coming in with autoimmune diseases and a lot of diseases that really seemed like sort of adult-onset diseases, chronic diseases. I was seeing a lot of things resulting from diabetes or obesity. I’ve always been interested in nutrition and lifestyle, and so seeing these kids coming in with chronic diseases really made me feel like there had to be a better approach to medicine and to healthcare. And then along the course of having some of my own medical issues, I actually came across functional medicine, came across your blog, Chris, and then podcast, and that’s where I really started diving into functional medicine and learning everything I could about it. It just seemed like such a better fit for me, as well, both as a patient and a practitioner.

Chris Kresser: Mm-hmm.

Dr. Amy Nett: Fortunately, you had a job posting for wanting to bring in another clinician to help you with your practice, and as far as I’m concerned, things worked out and here I am. I started training with you, I think it was about a year ago now, I think March or April of last year, and starting seeing my own patients. I think it was October/November that I started seeing patients, and I’m now increasing that practice.

Chris Kresser: Yeah, we’re really lucky to have Amy. She was the one we chose. I mean, I think we received over a hundred applications and reviewed probably 10 or 15 very carefully and did a whole round of interviews, and Amy was the one we chose, and we’re really lucky to have her because she’s extremely diligent in her research. She’s research oriented, and of course, that’s very important to me and to Dr. Schweig because it’s a big part of our work. She’s a very fast learner and has just really kind of jumped in and gone deep into the study of functional medicine. We work very closely together. She observed virtually all of my appointments for a long time before she started seeing her own patients, and we talk pretty much every day and review cases, and it’s just been great to have her support and be able to treat more patients and to offer more support to my existing patient base, and we’re really glad to have Amy.

Let’s jump in and talk. We can kind of think about this as Methylation 101 or Methylation for Dummies. Let’s talk a little bit, Amy. Why don’t you give people a kind of basic primer on what methylation is? And then we’ll go into talking a little bit about the processes in the body that are affected by methylation.

Dr. Amy Nett: OK, sounds good.

It’s important to realize that, in some respects, methylation is actually very simple, in that it’s really just a biochemical process. But it’s also a very intricate process that is absolutely central to our physical, emotional, and mental well-being. It’s essential for the optimal function of almost all your body systems. It occurs probably billions of times every second. In doing so, it helps repair your DNA on a daily basis, it helps keep inflammation in check, it replenishes the compounds needed for detoxification, and it helps maintain a stable mood.

Chris Kresser: Yeah. It’s interesting. One of the reasons I think methylation is hard to describe is that there’s not much it’s not involved in, you know?

Dr. Amy Nett: Yeah.

Chris Kresser: And when you’re talking about a process that is so ubiquitous and so important, it’s almost like saying, well, why is breathing important? Or why is blood flow through your arteries and veins important? But as you pointed out, it helps to really just think about all of the physiological things that you mentioned: repair of DNA, keeping inflammation in check, detoxification, and mood. I think if you want to highlight a few areas that methylation is crucial for, those are probably the ones that stand out.

Dr. Amy Nett: Of course. Yeah, so if we turn to thinking about the different processes in the body that are affected by methylation, we mentioned, in particular, mood. If we look at how methylation supports the brain and nervous system, we can think about at least two different functions where this works. One is in neurotransmitter synthesis and degradation, and this is really important in stabilizing mood and improving stress resilience. For some of our patients, one of the tests we do is looking for genetic predispositions as they relate to methylation, and one of those is COMT. Patients who have this mutation may have a more difficult time recovering from a stressful event. We know that if someone experiences something stressful, whether that’s a deadline at work or conflict with another person, it could actually take them longer to return to baseline because they don’t metabolize those sort of stress neurotransmitters, like epinephrine and norepinephrine, as rapidly as someone might without this mutation or without impaired methylation.

Chris Kresser: Mm-hmm. So let’s talk a little bit about DNA, too, because, of course, arguably one of the most important functions of methylation is affecting gene expression.

Dr. Amy Nett: Methylation does absolute affect gene expression in a few different ways. One of the topics that’s increasingly being discussed is the area of epigenetics, which is differences in individuals that can’t be explained by genetic differences alone. Methylation is one of these major factors in epigenetics, which means that it helps to explain why, for example, identical twins who have an identical genetic code may have a slightly different appearance or could actually suffer from different diseases.

Chris Kresser: Right, and that’s even true in diseases that are highly heritable, like schizophrenia.

Dr. Amy Nett: Yeah.

Chris Kresser: In identical twins, there’s a 50% concordance rate, which means there’s a fairly high likelihood that if one twin has it, the other one will have it, but it’s not 100%, and epigenetics and, of course, the environmental factors that affect epigenetic expression are probably what make up that difference.

Dr. Amy Nett: Right, exactly. And when we think about how methylation does this, I think it can be difficult for patients sometimes to sort of visualize what methylation actually is, so I think it could be worth saying that methylation is a term that comes from biochemistry, and you can think of methylation as the body essentially adding a tag or sort of like a work order to parts of DNA, maybe a gene or to a vitamin or an enzyme, and by adding that tag or what’s technically called the methyl group — which is why it’s methylation — when this tag gets added to that gene, vitamin, or enzyme, it actually changes the function. And in the case of DNA, by adding this methyl group or this tag, however you want to think about it, you’re actually turning genes on or off. This can be referred to as gene expression. The way in which methylation affects our DNA is incredibly important, and again, one of these reasons is because many of us have genes that predispose us to certain diseases, like cancer or, as you mentioned, maybe schizophrenia. But by turning these genes off, they’re not expressed, so we may be able to actually reduce our risk of developing certain diseases, some types of cancers, by optimizing our methylation.

Chris Kresser: That’s really, really crucial to understand because back maybe in the ’70s and ’80s, even into the early ’90s, there was a lot of excitement about sequencing the human genome, and there was a lot of fanfare around that and bold promises, like once we do this, we’re going to have the key to human disease and it’s going to lead to all kinds of medical breakthroughs and revolutionizing the treatment of chronic illness, and that just didn’t really happen. Our understanding now is that genes alone account for less than 10% of disease, and the exposome, which are all the environmental factors that an individual is exposed to from the moment of conception to when they die, the contribution of the exposome plus its interaction with genes and gene expression is really what accounts for 90% of the diseases that we’re dealing with. So here we have methylation as a process which really has a profound influence on the epigenetic expression of genes, which really boils down to determining our risk of chronic illness. I mean, that’s really what we’re talking about here.

Dr. Amy Nett: Absolutely, and this is something that we can modify, and that’s why a lot of times we want to do everything we can to really optimize our methylation, because as you mentioned with genetics, there are some things that we can’t change, but certainly those may often be really the minority of what contributes to certain diseases, and methylation is absolutely something that we can support through a number of different means.

Chris Kresser: All right, so let’s talk a little more specifically about what the physiological processes are in the body that are affected by methylation and then what can go wrong.

As we’ve already discussed, almost all the body’s systems are affected by methylation, or the addition of the methyl group, to be specific. So therefore, as one might expect, the signs and symptoms of impaired methylation are pretty vast, but they can be broken down into a few key categories, so let’s go over those one by one.

Dr. Amy Nett: Yes, as you mentioned, since almost all of the body’s systems are affected by methylation or, as we said, this addition of a carbon group, the signs and symptoms of impaired methylation are pretty numerous. Something I want to say we probably see more commonly with patients coming to the clinic is that methylation can be associated with production of important compounds needed in cellular energy production and metabolism, so oftentimes we might see patients presenting with fatigue or decreased exercise tolerance. Sometimes this means that people might have a more difficult time losing weight.

Chris Kresser: Yeah. Cellular energy production is crucial not only just for our experience of energy, but also, of course, the function of cells because all cells require energy to function and the body is just made up of cells. But one of the other key symptoms of impaired cellular energy production — or mitochondrial dysfunction is another way of talking about that — is pain. People who have chronic pain, like fibromyalgia type of symptoms, or people who have chronic muscle aches or you mentioned exercise intolerance, Amy, which means if they just do a small amount of exercise, they feel really wrecked after that and have a difficult time recovering, that’s something that we would expect to see with this disrupted cellular energy production related to methylation.

Dr. Amy Nett: Yeah, and when you talk about methylation and exercise, there was actually an interesting study that looked at how exercise does affect methylation, and the study found that exercise actually increased the expression of genes associated with energy metabolism, insulin response, and inflammation within the muscles. It was interesting to hear that exercise benefits muscles not just from the physiologic benefits of using them, but also by actually changing the genes that are expressed within the muscle.

Chris Kresser: I love that study because it’s just a perfect example of what we’ve been talking about. We’ve been focused on the sort of biochemical and physiological effects of something like exercise, but now we’re learning that it doesn’t just have a mechanical effect. It’s actually altering gene expression, which, of course, again is part of why exercise reduces the risk of so many different diseases.

Dr. Amy Nett: Yeah, it’s pretty amazing, the cascade of benefits that you can get from exercise.

Chris Kresser: Yeah. Let’s talk a little bit about brain and nervous system function because that’s another big area where methylation plays a role.

Dr. Amy Nett: Yeah, and we talked a little bit about the role of methylation in terms of promoting synthesis and degradation of neurotransmitters and stress resilience, but methylation is also really important in supporting myelin. Myelin can be thought of as the sort of protective coating or insulation along the nerves. So if you have injury to your myelin, you can almost think of this like having frayed electrical cords that have vulnerable and exposed wires. Methylation is important in helping to maintain the integrity of the myelin, and maintaining a healthy nervous system is really one of the best things we can do to support mood and cognitive function. It’s actually injuries to the myelin that underlie changes seen in multiple sclerosis, so an incredibly important structure in the nervous system.

Chris Kresser: Yeah, this is crucial, and we see so many patients with neurological issues ranging from just kind of mild neuropathy, numbness or pins and needles, tingling in the peripheries like the hands and feet, to more serious conditions like multiple sclerosis. And of course, those are multifactorial conditions, so we’re not saying that methylation is the only factor with these conditions, but it often is at least one factor, and people do tend to improve if they have impaired methylation and we give them some support.

Dr. Amy Nett: Yeah, and that’s really important to emphasize, that methylation is a very important piece in the puzzle, and I think it’s rarely the single answer, particularly in these complex issues, of course, like multiple sclerosis, very multifactorial, but methylation is one of those foundational pieces that is just best to optimize.

Chris Kresser: Right, and we’ll probably get into this a little more later, but another thing worth thinking about is impaired methylation can cause a lot of problems, but there are also a lot of problems that can mess with methylation! As usual, it’s a little bit of a chicken-and-egg situation, where, for example, if you have SIBO or other gut issues or nutrient deficiencies, those are going to impair methylation. So sometimes focusing on methylation is the right step, other times fixing all these underlying problems that can cause poor methylation in the first place is the right step, and other times doing both at the same time, which is probably more often what it tends to look like in our practice, is the right way to do it.

There are a couple more things I think we should talk about as far as methylation goes, and that’s detox capacity and immune function.

Dr. Amy Nett: Yeah, and I think detoxification is one of the most important roles that methylation plays in our body. Specifically, methylation helps to remove toxins from the body, so having impaired methylation can actually block or inhibit detoxification. As a result, you may have a higher heavy metal burden, which could lead or at least contribute to something like mercury toxicity, or you may have a more difficult time recovering from something like SIBO or chronic yeast overgrowth. And while we’re sort of promoting optimizing methylation, it’s important to realize that you can also over-methylate.

Chris Kresser: Mm-hmm.

Dr. Amy Nett: It can sound like this incredible answer, and if often is, but when we do appropriate tests and we find that someone might benefit from methylation support, we do caution all of our patients to start methylation support slowly. One of the reasons is because improving methylation will actually lift the block on detoxification, and as a result, toxins can move into the bloodstream, activating cell-mediated immune response, and that can overwhelm your detoxification, making you feel as though you have sort of a flu with fatigue, malaise. So starting methylation support should be done slowly and looking for these symptoms of increased sort of detox symptoms.

Chris Kresser: Yeah, that’s a great point. We see that regularly in our practice with people as they become more able to detoxify, and methylation also would increase — as we’re about to discuss — their ability to fight intracellular infections, for example, chronic viral infections or other infections. If all of a sudden you make all that function better, you could definitely feel worse, and so it’s important if you’re doing any kind of methylation protocol, especially if you’re doing it on your own, to move slowly and not overwhelm your detox system because that’s not going to be helpful in the short term or the long term.

The other thing is immune function, and I think both detox capacity and immune function are maybe two of the more important aspects of methylation, especially today when we’re seeing such a proliferation of autoimmune conditions and when we find ourselves living in a world where there’s more exposure to environmental toxins than we’ve ever had before in human history by orders of magnitude.

With immune function, I’ve talked a lot in the past about the importance of maintaining healthy T regulatory cell function, cell-mediated immunity, the ability to fight off infections. If you find yourself catching every cold and flu that comes through town, then it may be that methylation is impaired or not functioning optimally for you. And there is some research linking poor methylation to autoimmunity, so it’s just another consideration. If someone’s having a lot of problems with immune function, that will be an invitation for us to consider methylation as one thing that’s possibly going wrong.

I know that’s a lot that we just shared. I hope that wasn’t too far off the 101 or “for dummies” theme there. Why don’t we just list and talk about some of the symptoms that are associated? We’ve mentioned a bunch already, but it might be helpful just to do a list so that people can find themselves in this.

Dr. Amy Nett: Well, there’s a pretty broad range of symptoms and conditions that can be associated with poor methylation, and I think, as you just said, we’ve already mentioned quite a few, but I’ll mention some of the more common signs and symptoms we see with our patients presenting who end up having methylation issues. Fatigue, as we mentioned, that can be a really common sign of poor methylation, just not having energy, not having cellular energy production. We also see obesity can sometimes be related to impaired methylation. Infertility and recurrent miscarriage. We also see, as we mentioned, there are a lot of nervous system manifestations. So that might be something like anxiety, depression, sometimes insomnia or other sleep disturbances, and even some of the more severe neuropsychiatric disorders, such as bipolar disorder, have been linked to certain methylation issues, whether genetic predisposition and also impaired methylation resulting from that.

Chris Kresser: That’s a good list, and as Amy said, it’s not complete. So if you’re suffering from a lot of those symptoms, it could be that methylation is playing a role. If you didn’t hear some of your main symptoms, it doesn’t necessarily mean that methylation is not playing a role. Of course, a lot of the symptoms that we mentioned are pretty nonspecific, which means they could be caused by any number of things. Almost that entire symptom list could be caused by gut issues alone. So you can never really make a diagnosis based on symptoms alone, which is why we tend not to pay as much attention to symptoms in functional medicine as in other approaches, but that should give you a general idea.

Let’s move on and talk a little bit more about why methylation goes south in the first place. I think this can really be broken down into two categories, which are genetic predisposition and diet and lifestyle factors and also disease states or health problems that can influence methylation. Why don’t you start us off with a discussion of genetics?

Dr. Amy Nett: OK. I want to take at least one or two minutes to mention MTHFR, because when I speak with our new patients who are coming to the clinic, a lot of patients come in and they’ve heard methylation, they’ve heard this buzzword, they know it’s important, and so often they’re excited to tell me what they’re MTHFR is. So they come in and they say, well, I know I’m already heterozygous for A1298C or C677T. MTHFR seems to be what’s most popular out there right now, but it’s important to know that there are at least a dozen other genes that are associated with methylation. For those of you who haven’t heard of MTHFR, MTHFR stands for methylenetetrahydrofolate reductase.

Chris Kresser: Thank God for the acronym.

Dr. Amy Nett: Yeah, that is a mouthful. We’ve said it once, so from here on out we’re going to stick with MTHFR. So MTHFR is one gene that’s involved in the methylation cycle, and it probably is the main driver of methylation, and specifically, it makes methylfolate, but again, when we’re really looking at methylation, we need to consider all of the genes — so over a dozen genes — that contribute to the methylation cycle.

Chris Kresser: Yeah, and since this is a 101 podcast, I don’t think we’re going to go into a lot of detail on those other genes. It starts to get pretty complex. I think the takeaway here is that there are genetic mutations that do affect your likelihood of developing methylation problems, and the MTHFR gene is one of those and perhaps the most important, but there are many others that play a significant role as well.

Other than genes, what else can we talk about that disrupts methylation?

Dr. Amy Nett: Well, Chris, I think that’s really important because I’ve heard you say before — and this is so true, so worth repeating again — that genes load the gun, but environment pulls the trigger. Genes give us information in terms of helping us know where to look for potential problems in the methylation cycle and maybe helping us to tailor treatment, but really it’s the lifestyle, diet, and disease states that are probably more important in knowing how someone is actually methylating. So we need to consider a patient’s internal and external environment in addition to the genetic predisposition to really understand their functional methylation or how they’re actually methylating.

Chris Kresser: Yeah, let’s drive that home even a little bit more.

Dr. Amy Nett: Yeah!

Chris Kresser: Because as you know, this is a pet peeve of mine, and there are websites out there where you can connect your 23andMe results and they will spit back your methylation genetic profile along with a list of supplements that you should take solely on the basis of the genetic mutations that you have. And where you can start to see the limitations of this approach very quickly is that oftentimes with those computerized algorithms one mutation suggests that you would tolerate methyl donors like methylfolate really well, and so they’ll list those out next to that mutation, but then another mutation you have further on down suggests that actually you wouldn’t tolerate those methyl donors, so it tells you to avoid methyl donors. This is just one example and one reason why we cannot rely on the genetic profile alone to tell us what’s actually happening in the methylation pathways.

Amy and I have seen numerous cases where somebody has no really significant mutations in MTHFR or other significant methylation-related genes, but when we go and do some functional methylation testing, which we’ll come back to in a little bit, they’re kind of a disaster. They’re having huge problems with methylation. Then on the other hand, we’ve seen patients who have mutations where you would expect them to be pretty challenged in terms of their methylation, but when we do a functional profile, they’re actually methylating really well.

I’m homozygous for MTHFR C677T. Again, that’s a mouthful, but it means I have a mutation in MTHFR which would predict that my methylation doesn’t work well and that I would really benefit from methylation support, but I’ve done a lot of functional testing on my methylation, and in almost all cases, the results have been very clear, and I’ve experimented a lot with all kinds of different methylation support, and I just don’t really feel that different when I do it. So it’s really important to consider this and to not get too caught up in what the genetic mutations are without doing that functional testing.

Dr. Amy Nett: Yeah, and as you said, this is probably a good reason to work with a practitioner if you do suspect impaired methylation and want to focus on that, because right now the research on methylation is so new and there’s a lot of new information coming out, and trying to read on the Internet what you should be doing about methylation, I think, can present a lot of conflicting information right now. So it’s probably best to work with someone who has some experience.

Chris Kresser: Yeah, some early pioneers in the methylation world were working a lot with kids with autism and some pretty specialized populations, and they developed some really interesting theories about the significance of various mutations, and there’s unfortunately very little peer-reviewed research, if any, to support some of those ideas. Lack of proof, as they say, is not proof against, but there have been some challenges to some of what’s been presented, for example, the idea that up-regulation in a gene called CBS leads to high levels of sulfate and glutamate and alpha-ketoglutarate and taurine and other substances in the urine. The treatment for that, according to this theory or approach, is to reduce your consumption of animal protein. When I heard about all that, I was pretty reluctant to just jump in because I know if you eliminate animal protein you’re going to be adding something else, right? And it’s probably going to be a lot of grains and carbohydrates and things that a lot of people don’t feel good on. So when I dove in and did a lot more research, I found that there really wasn’t any peer-reviewed research to support that interpretation and there were actually some basic problems with the way that that was being explained. Again, it’s just another reminder to be careful with how you interpret all this information and not ascribe too much importance to the genes.

I think we’ve beat that horse to death! So we can probably move on and talk about what else affects methylation since we’ve, I think, made it abundantly clear it’s not only genes.

Dr. Amy Nett: OK, so now that everyone’s in agreement that we’re not going to treat methylation based solely on genetic predisposition, probably the more important factors affecting methylation are largely under our control, diet and lifestyle related. Of course, poor diet is something that’s going to impair methylation or tax the methylation system, and this is in part because if you’re eating a standard American diet or a diet that includes a lot of processed and refined foods, that’s going to be contributing to inflammation. You’re probably going to have inadequate nutrients, maybe insufficient B vitamins, zinc deficiency, or even magnesium deficiency, and all of these vitamins and minerals are important cofactors in supporting the methylation cycle.

Chris Kresser: Yeah, that’s crucial. And we know from studies that a shocking percentage of Americans are deficient in all kinds of different nutrients, so this is a real problem and, I think, one of the biggest. And even people who are doing really healthy diets can often be deficient, as we’ve seen, Amy, and that’s because of things like SIBO, low stomach acid, leaky gut, which impairs nutrient absorption and increases inflammation in the gut barrier, so even those of us who are following a really great diet, if we have one of these gut issues going on, we’ll see deficiencies of nutrients. And we do organic acids testing and other kinds of nutrient status testing where we do see this even with people who are following a good diet.

Dr. Amy Nett: Absolutely, and any sort of chronic gut issue, as you mentioned, leaky gut, chronic infection, will impair nutrient absorption and also impair methylation. Similarly, having a chronic infection is also going to contribute to an overburdened detoxification system. Having an overburdened detoxification system is something else that might impair methylation. That could be coming from environmental toxicity, heavy metals, maybe mercury toxicity, or high copper levels.

Chris Kresser: Mm-hmm. Yeah, pesticides, fungicides, volatile organic compounds, phthalates — there are so many things now that we’re exposed to that we really weren’t for the vast majority of our evolutionary history. And because of that, we didn’t really evolve efficient defense mechanisms to deal with those kinds of toxins, whereas with some of the food toxins, we’ve been exposed to them forever, and so we have fairly effective ways of dealing with them, and that’s not really the case with environmental toxins.

I know we’re getting a little short on time here, so there are a few other things I’m going to quickly go through. Stress and lack of sleep — big surprise! Pretty much any discussion of any health problem, we know that stress and lack of sleep are going to make those worse. We have a variety of medications, like antacids because of their effect on stomach acid and nutrient absorption. Methotrexate, metformin, contraceptives, blood pressure meds — all of these can affect levels of B vitamins, which play a crucial role in methylation.

The last thing we should probably talk about — and this is a relatively new cause of methylation issues — is taking too much methylation support, too many methylation supplements. This can cause over-methylation, where you end up with feedback inhibition and reducing the body’s internal production of methylfolate. It’s kind of like if you take testosterone cream and you’re a guy and you eventually reduce your body’s own ability to produce testosterone. It’s a similar kind of mechanism.

We’re going to move on to talk a little bit about how we test and treat methylation. Yeah, why don’t we start with testing, Amy, what we’re doing right now in the clinic?

Dr. Amy Nett: OK. As we mentioned again, MTHFR seems to be the most commonly tested gene. When patients come to us and they’ve worked with other practitioners, they often know what their MTHFR is, but we prefer to do testing right now through 23andMe because they provide the most comprehensive genetic profile as it relates to methylation. I think one thing that’s important to note is that sometimes patients are reluctant to be tested through 23andMe because they have a concern that they’re going to get an abundance of genetic information, some of which might tell them that they’re predisposed to something like Alzheimer’s or Parkinson’s. But the way we do this testing, we have patients order a test kit through 23andMe. It’s a saliva test, so you collect a small sample of saliva, send it back to the lab, and then once those results become available, we have our patients run them through GeneticGenie.org. You do the methylation analysis, and that way you’re only getting the genes as they relate to methylation. Because it’s completely reasonable; we don’t necessarily want to know our genetic predisposition to things that we have no control over, but here we’re just looking at genes as they relate to methylation.

Chris Kresser: And I question even what those numbers are, I mean, because those are just averages. If it says you have this gene and you have 120% higher risk of Alzheimer’s, well, they’re just looking at the general population following a standard American diet and lifestyle that has those genes. And yes, those people may have that higher percentage risk based on those genes, but that doesn’t mean you do if you’re following a paleo type of diet and lifestyle. It’s a very tricky area, and for a lot of people, we just generally don’t even recommend getting that kind of information. And 23andMe doesn’t even offer it anymore, so you can’t get it even if you wanted it.

There are other services that you can plug your 23andMe raw data into to get more comprehensive methylation gene reports, and some of those, I think, can be valuable, but there’s also a lot of data that we just don’t know what to do with yet. The reason I like Genetic Genie is it focuses on the mutations that we know the most about and that are the most actionable, and particularly if people are trying to figure this stuff out on their own, which is already really difficult, using those more complex reports can be challenging because not only do you have to consider each mutation individually, you have to consider how the various mutations interact with each other and sometimes cancel each other out or sometimes amplify each other. So that’s a whole other level of understanding, and it’s an example of why this can be so difficult.

In addition to the genetic testing, I mentioned before that we do functional methylation testing, so let’s talk a little bit about that.

Dr. Amy Nett: Yeah, functional methylation testing, it really provides complementary information to what we’re getting from the genetic information about methylation. I think there are at least two labs that I know of that are offering functional methylation panels. I think it’s Doctor’s Data, and then we more commonly use the HDRI or Health Diagnostics and Research Institute functional methylation pathways panel. That way we’re looking at a number of different folate metabolites because folate is really crucial in the methylation cycle at several points, and we also get a look at several markers that somewhat tell us about detoxification. We look at oxidized and reduced glutathione and several markers for oxidative stress as well, so we really get a sense of how that person is methylating, the degree of oxidative damage they have, and if they need detoxification support as well.

Chris Kresser: Right. So think of it this way: The 23andMe data genes tell you what your predisposition is, what the likelihood is that you’ll have problems methylating, but it doesn’t tell you anything about what’s actually happening in this moment right now for you. And that’s where the Doctor’s Data methylation panel or the HDRI methylation panel comes in, because that gives us the actual status of your methylation by looking at a whole bunch of different compounds that are involved in the methylation cycle.

But above and beyond that, there are a whole bunch of other tests that we can do that either indirectly or directly can tell us about methylation. For example, one is a urine organic acids test, and on that test there are markers for active B12, methylcobalamin or adenosylcobalamin, and active folate, methylfolate, deficiencies. So if we see those markers triggered, that might tell us that someone’s not methylating well, and it might spur us on to do the HDRI test. Organic acids also has markers for cellular energy production and neurotransmitter metabolism and degradation and also detoxification, which, as you’ll recall from the beginning of this show, those are all major areas that are affected by methylation. So if we do an organic acids test and we see problems in one or more of those areas, then that can tell us that we should do some additional testing for methylation.

What else, Amy?

Dr. Amy Nett: Some of the additional tests we might also consider might be a urine amino acids test. When we were talking about neurotransmitters, well, amino acids are the building blocks for neurotransmitters, so oftentimes understanding the amino acid imbalances allows us for more targeted treatment.

Chris Kresser: Yeah. There’s some testing now, like biopterin and neopterin, which can help assess the probability of a chronic infection or inflammatory cytokine stimulation, which can affect the whole methylation cycle. There are tests for nutrient deficiency. That also comes up on the organic acids test, various B vitamins that are cofactors in the methylation process. Of course, gut testing, which we mentioned earlier that leaky gut, SIBO, malabsorption, and low stomach acid can be a risk factor for methylation. Testing for chronic infections and heavy metal toxicity that could impair or slow down methylation. So a lot of the tests that we normally run in functional medicine can be relevant here, and then there are some specific ones that we might follow up with after we do some methylation testing, depending on the specific genes that are mutated or specific things that we find on the HDRI panel.

OK, so finally let’s talk a little bit about how we address and support methylation.

Dr. Amy Nett: Sure, and I think, again, just to mention this because it’s so important, for most people, each of the steps in methylation can be affected by diet and stress management. So eating a nutrient-dense, low-inflammation paleo diet can really support healthy methylation, as well as doing stress management, whether it’s daily progressive relaxation, sitting meditation, yoga, tai chi — doing something to really help manage stress. For most people, that’s going to optimize methylation. Most often the people who have come to our clinic do have something else going on and do require additional support to get methylation back on track. It’s not an indication that they’re going to be on methylation support forever or as a long-term requirement, but oftentimes we just need to sort of kick start the methylation cycle again.

Chris Kresser: Right. That’s a really important point because we often get questions from patients: Well, if my methylation is messed up and I have to do this protocol, do I have to take it for the rest of my life? And almost invariably the answer is no. It may be that if someone has pretty significant mutations, they’ll need some level of methylation support on an ongoing basis, but it’s rarely going to be the full protocol that we use initially.

Dr. Amy Nett: Right. The most important thing we do when addressing methylation, as you’ve already mentioned, is we make sure there are no other underlying contributing factors, so we always make sure we’ve tested gut, tested for metals. But then when we do realize we need to support methylation and we’ve done the appropriate testing, we provide a specific combination of B vitamins because those are the crucial sort of cofactors or nutrients needed in the methylation cycle. We generally also provide some liver or detox support and often provide cell membrane support, something like phosphatidylcholine, to help support cell membrane integrity.

Chris Kresser: Right. Those of you who have been following my work for a while, you’ll probably recall or hopefully you’ve read the article on the differences between folate and folic acid. This can be confusing, and if you want to brush up on it, you can just google “Chris Kresser, folate and folic acid.” But as a reminder, if you’re kind of thinking, oh, I have a supplement and it has some folic acid in it, so this is helping me with methylation, remember that folic acid is the synthetic form of folate and has to undergo a number of conversions before it can be effectively used in the body and in the methylation cycle, and a lot of people don’t do that conversion well, especially people with certain mutations related to methylation. So we’ll generally use the more active forms, a combination of folinic acid, which is kind of the intermediately active form, and methyltetrahydrofolate, which is the more active form, 5-MTHF. These enter the methylation cycle at different places and can have quite a different effect. Especially if people have mutations that suggest that they might not tolerate the fully methylated forms of either B12 or folate as well, the intermediate forms, like folinic acid in terms of folate or like hydroxocobalamin in terms of B12, can be really important.

Dr. Amy Nett: Yeah, exactly. Then once we’ve had someone on support for maybe a couple of months and we’ve treated any additional underlying conditions, whether it’s SIBO or other gut dysbiosis, we will repeat the functional methylation testing. So if someone’s been on our methylation support, we’ll see if they have sort of recovered, and if the parameters on that test look better, then we’ll start actually weaning patients off of the methylation support. Because as you said, it’s extremely rare that someone’s going to need methylation support long term.

Chris Kresser: Yeah, as we’ve talked about on the show numerous times, it’s a lot easier to maintain a system that’s already in balance than it is to get it back into balance in the first place. The heavy lifting is getting it back into balance, and then once it’s in balance, you typically need less of everything to keep it there. That’s not only how it works with methylation support, but also gut treatment and many of the other treatments that we do.

Before we finish up, I want to let all of you know that Amy is starting to accept new patients again. When we first launched her practice at the end of last year, she filled up really quickly and had about a four- or five-month waitlist, I think, which she’s now mostly worked through. So there are some spots starting to open up in her schedule, and I really recommend her for anybody who’s looking for help with not just methylation, but any of the issues that we deal with in a functional medicine practice — chronic fatigue, gut problems, autoimmune conditions, mood disorders, skin issues, hormone and reproductive issues for both men and women, any kind of chronic illness, which functional medicine is fantastic for, of course, especially when you approach it from an evolutionary perspective.

Amy, I have so much confidence in her, and in the year that we’ve worked together, I’ve just been so impressed with her capacity to absorb new information and put it into practice immediately. She’s studied very closely with me over the past year, observed virtually all of my appointments. We’ve had lots and lots of training sessions. We talk almost on a daily basis, and she checks in with me regularly. If she has any questions about a patient’s care, she’ll come to me, and I’m in contact with her, like I said, on a regular basis. So you get the same quality of care through Amy that you get when you come to see me, and it’s exciting for me to be able to help more people with Amy on board and to provide more support for my own patients for follow-ups with her on board, and I can’t recommend her enough.

So if you’re interested, you can go to CCFmed.com. That’s the California Center for Functional Medicine website. Click on the New Patients tab in the upper right, and then click on the section that pertains to working with Amy and me to learn a little bit more about how we both work with patients. Then there’s a link there to a form where you can apply to become a new patient. Definitely do that if you’re looking for some help.

One advantage to working with Amy is she can work with patients all over the continental US, whereas I’m only accepting patients who live in California at this point. You will have to come see Amy in person for the first appointment. That’s just a requirement of the medical board. But you can do your follow-ups via phone or Skype. Because of the licensing situation here in California, she’s able to accept patients from all over, whereas I’m a little bit more limited right now. So yeah, CCFmed.com.

Amy, thanks for coming on the show. It was great. We’ll definitely do this again. Yeah, I hope you had a good time, too.

Dr. Amy Nett: Yeah, that was great, Chris. I think we covered a lot, and hopefully we kept it simple enough, but yeah, I think we could probably fit in a few more of these about methylation and still get into some more detail. There’s a lot going on with methylation that’s exciting research to follow.

Chris Kresser: Absolutely. And this is just a teaser, but in the next few weeks, we’re going to be launching a new series called From Chronic to Cured, which explores how we use functional and evolutionary medicine to treat chronic illness, and it’s going to consist of podcast episodes, blog posts, and even free webinars. I’ll lead some of the episodes. Amy will lead some. Dr. Schweig, my co-director at the California Center for Functional Medicine, will be involved. I’m really looking forward to it because we’re going to be able to share a lot more about our process, how we approach diagnostics and treatment with a whole range of conditions that we’ll feature in the series. We’ll share case studies. I think it’s really going to help bring this to life for some of you. We’ve talked about a lot of these things over the years, but to be able to share some case studies from our clinic and really go a little bit deeper into how we’re approaching this stuff is, I think, going to be really helpful for both patients and clinicians alike. We’ll make an announcement about that on the blog soon.

Thanks, as always, for listening. I’m really grateful that you’re a part of this community, and if you appreciate and enjoy the show, head over to iTunes and leave us a review. It really helps us out and brings new listeners to the show, and we can change more lives that way. Have a great couple of weeks, and I will talk to you then.

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http://www.thekitchn.com/feedburnermain

I feel nostalgic for the good old days when avocado toast was something novel, a little breakfast secret to share with friends. Avocado toast these days, well, it’s gone mainstream. But that doesn’t mean we should take it for granted. Avocados are a water-hungry crop, and with drought conditions being what they are, this wonderful fruit could get rarer and more expensive in the days ahead. So make that avocado toast count — every slice should be extra special!

Here are 11 delicious ways to upgrade your toast into a breakfast treat that is worthy of the avocado itself. And all you need are two ingredients to make any one of these fancied-up avocado toasts.

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Originally posted at: http://www.nerdfitness.com/

This is a recipe from NF Rebel Chef Noel.

Today we’re going to be looking at a recipe that is super easy to make, but looks really elaborate and impressive.

Maybe you’ve invited someone special over to cook dinner with you. Or heck, maybe you just want to treat yo self to a nice meal because it’s Thursday, you work hard, and damnit, you deserve it.

Well, look no further!

I’m all about fancy-looking recipes that take a minimal amount of time. Most of us Rebels work a full-time job, some of us have families, and on top of all our daily responsibilities, we’re doing our best to get and stay healthy. Steve always says 80% of winning this game is diet, so why not make this part as easy as possible?

This recipe should take no longer than 30 minutes, depending on your knife skills. And you can get to dinner time even quicker by making the pineapple salsa ahead of time!

Pan Seared Salmon and Pineapple Salsa

Prep time: 18 min
Total Time: 30 min
Servings: 4

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Ingredients:

For the salsa:

  • 1/4 avocado
  • 1/4 pineapple
  • 1/4 onion
  • 3/4 bell pepper
  • 1/2 jalapeno – or more if you like it spicier! Bonus point if you roast the jalapeno first!
  • 1 clove garlic – minced
  • 1 tsp (5ml) lime juice
  • 1/4 (1.23ml) tsp salt

Optional ingredients:

  • 1/4 tsp (1.23ml) red pepper flake
  • handful of chopped fresh cilantro

For the fish:

  • 1 lb (453g) salmon filet (wild caught preferred) – Ask the person behind the counter to cut your fish from the thickest part of the filet.
  • 1 tsp (5ml) coconut oil (for pan-frying)
  • salt & pepper to taste

Equipment:

  • knife
  • cutting board
  • small mixing bowl
  • spoon
  • measuring spoon
  • frying pan

Instructions

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Note: The instructions below are for a simple raw pineapple salsa that should only take as long to make as it does for you to chop the ingredients and mix them together with a spoon.

(That’s pretty quick!)

If you have more time (or are a more advanced cook) and would like to deepen the flavor of your salsa, throw everything but the garlic and avocado on the grill or in the oven to roast them a bit before chopping!

We’re going to start off by washing and chopping our vegetables.

1. Dice your bell pepper, jalapeno, and 1/4 of your onion. Here is a picture of what mine looked like, so you can see about what size they should be. If they’re not exactly that small or you want to cut them a different size, that’s fine. Totally up to you!

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Once you’ve finished chopping them, add them to your mixing bowl.

2. Smash and mince (cut really small) your clove of garlic. Add that to your mixing bowl as well.

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3. Now cut your avocado. First, cut it in half.

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Then, make slices vertically down one of the halves. (I chose the half without the seed so I wouldn’t have to take out the seed right then.)

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Now make perpendicular cuts on the avocado short-ways.

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Lastly, use a spoon to scrape the avocado into your bowl with the rest of your ingredients. (I actually only ended up using only 1/4 of the avocado for the amount of salsa I was making. I ate the other 1/4 that was cut as I was cooking… no apologies.)

You can store the remaining avocado in a ziplock bag to use later. The outside will oxidize over night and look a somewhat yucky brown, but it is still edible, and you can use it the next day. Alternately, you can make a quick guacamole to dip veggies in and munch on as an appetizer!

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4. Now it’s time to cut the pineapple! I so rarely buy pineapples at the store, but luckily the day I went shopping, not only were pineapples on sale, but they were also ripe! Score!

If you can’t find fresh pineapple at the store, you can buy canned. Just read the ingredients to make sure there’s no added sugar!

First you’re going to want to cut the top off.

Noel_Pan_Seared_Salmon_012

Stand your pineapple up. You can see that it has a core inside. This is where it once attached to the bush it came from. You can sort of see a faint outline of it when you stand the pineapple up.

Make your next cut as near to the core as possible without cutting the core.

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After you’ve cut off your piece of the pineapple, lay it down again and cut off the bottom.

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Then, cut it in half. We’ll only be using this much for the salsa. Keep the rest as an after-workout snack, or add it to grilled steak kabobs, burgers, or grill it and use it as dessert!

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Now we’re going to carefully remove the skin. Get the knife as close to the skin as possible and slice it off.

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The first time I cut a pineapple, I cut too close to the fruit and lost most of it. Take it from me – don’t do that. It was disappointing.

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If you want to cut your whole pineapple right off the bat, a better choice might be to slice of the skin right after you cut the top off. Since I only used this portion of my fruit and saved the rest, I cut it this way.

If you have some indentations with the skin still in them (eyes) in your pineapple, that’s okay. This is edible, but not a nice texture to chew. You can carefully cut these pieces out with a smaller knife or chop them off after the next step.

Next, slice the pineapple into three long pieces (hot dog style). Then slice shorter, perpendicular cuts about the same size as the avocado pieces (hamburger style).

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Add this juicy, pineappley goodness to your bowl.

5. Now add your lime juice, salt, and any optional ingredients you might want. Mix all ingredients well and set aside.

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Now onto the fish!

6. Cut your fish into single serving sized portions. My 1 lb salmon filet sliced pretty nicely into 4 pieces. It might be tough to get your knife through the scales if your knife is not especially sharp. It was tough for me. Just keep at it and don’t cut yourself.

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The thickest part of my salmon was about an inch. At the thinnest, it was maybe a quarter inch. That’s okay. I cooked each piece of fish individually because I had a small pan. If you have a larger pan, you can cook all your fish on it at once – just remember to watch them carefully because the thinner pieces will cook much faster than the thicker ones.

7. Heat your pan on medium high heat with your fat (I used coconut oil) in the pan.

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8. When the pan is hot enough, carefully place the fish skin-side down in the pan. Do not drop or throw the fish! This will cause oil to splash up and burn you, and that is no bueno.

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9. Let this side of the fish cook for about 6 minutes. You’ll be able to see the salmon cook as the side nearest to the pan changes from a dark translucent pink to a pastel orange-y color. Press down on the salmon a couple times during cooking to keep the skin from curling up.

10. Carefully flip your fish using your spatula. Let the other side cook for another 5-6 minutes.

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You’ll see the orangey-pastel color increasing on this side of the fish and it will nearly come to meet the cooked other side of the fish. Press down this side a couple of times to prevent the sides from curling up.

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11. Once your larger surfaces are done, take a minute to turn the fish onto its sides for about 30 seconds each to sear these as well, then remove from heat.

Serve over a bed of fresh or wilted spinach, and spoon some of the salsa on top of each piece of fish. Serve by candle light while a salty sea breeze tousles your hair.

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Treat Yo Self!

You deserve a treat. And by treat, I don’t mean a pint of cookie dough ice cream while sitting on the couch watching Game of Thrones. What I mean is a decent meal, cooked by your own two hands, styled on a plate, served at a dinner table. Cooking a fancy meal can make you almost as proud as hitting a new PR on your deadlift.

Many of us are short on time and think of nice meals as a luxury. I’m guilty of this too. About 90% of my meals are eaten on the couch in front of the TV or computer. Most of my food is the same few dishes cooked over and over again.

I’ve said this before and I’ll say it again: Eating healthfully doesn’t have to mean baked chicken and steamed veggies for every lunch and dinner.

Take a chance, plan a couple days ahead, and eat something new! Invite a friend over to cook with you. Listen to your favorite Pandora station while you’re chopping. Treat yo self to a new piece of kitchen equipment you’ve been eyeing and try it out. Make it fun!

If we make cooking a relaxing treat, it can become an activity you enjoy. Even if you’re short on time, limiting your food options to recipes that take 30 minutes or less, prepping ahead of time, and using a minimal amount of easy-to-clean equipment can make learning this new skill less stressful and more pleasurable.

Try it out!

How do you make cooking an enjoyable activity?

Do you dedicate a certain day of the week or month to having dinner with friends or family?

Let us know in the comments!

– Noel

PS: We’ve been adding these recipes and a few dozen more to our Nerd Fitness Academy, which has recipes, meal plans, workout plans, and the ability to complete quests and missions and level up as you get healthier. Check it out!

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Mother’s Day falls during the most beautiful time of spring, when it’s just warm enough to be outside. Why not skip the gift this year and instead spend some quality time outdoors, with a picnic lunch?

A little relaxation is a simple way to pamper a mother of any age, but especially one with children still at home that keep her on the go. If you have a mama in your life — whether it’s a friend, a partner, or your own mother — a picnic to share a few smiles and sunshine is sure to fill her heart right up.

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pimg class=”alignright size-full wp-image-55399″ src=”http://cdn.marksdailyapple.com/wordpress/wp-content/uploads/2015/04/child-ipad.jpg” alt=”” width=”320″ height=”213″ /I#8217;ve been on a bit of a #8220;children#8217;s health and wellness#8221; kick lately, with a couple posts discussing the importance — and, unfortunately, dearth — of a title=”How to Raise Creative and Self-Reliant Free-Range Kids” href=”http://www.marksdailyapple.com/how-to-raise-creative-and-self-reliant-free-range-kids/”free play/a and a title=”Are We Thwarting Our Children’s Instinct to Explore?” href=”http://www.marksdailyapple.com/are-we-thwarting-childrens-instinct-to-explore/”exploration in our children#8217;s lives/a. Some of you have speculated via email that Carrie and I have something to announce, but that#8217;s emdefinitely/em not the case. This is simply an important topic for everyone with a stake in the future of this world. The mental, physical, and spiritual health of our children today will determine our trajectory through history in the decades to come. If a fat, sick, and unhappy generation takes the reins of this planet, nothing good will come of it./p
pspan id=”more-55115″/span/p
pAlso, those are emour kids/em. Once you#8217;ve popped one out, it#8217;s your responsibility to give them […]

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pBefore we get to today#8217;s regularly scheduled post, I just wanted to give you this friendly reminder: stronga title=”Thrive Market Special” href=”http://thrv.me/sissongift” target=”_blank”THIS/a/strong limited-time offer strongends today, May 6!/strong/p
pRegister to a title=”Thrive Market Special” href=”http://thrv.me/sissongift” target=”_blank”win a $500 shopping spree to Thrive Market/a (no purchase required), and stock up on all your paleo/primal necessities at Thrive Market to claim your free gifts, including a 2-month free trial membership, $10 off your first order, 3 new Primal eBooks, a Primal Blueprint best-selling cookbook, and a $10 Coupon to PrimalBlueprint.com!/p
a title=”Thrive Market Special” href=”http://thrv.me/sissongift” target=”_blank”img class=”alignnone wp-image-55403″ src=”http://cdn.marksdailyapple.com/wordpress/wp-content/uploads/2015/05/Screen-Shot-2015-05-06-at-1.25.25-PM.png” alt=”” width=”540″ height=”129″ //a
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a title=”Thrive Market Special” href=”http://thrv.me/sissongift” target=”_blank”img class=”alignnone wp-image-55402″ src=”http://cdn.marksdailyapple.com/wordpress/wp-content/uploads/2015/05/Screen-Shot-2015-05-06-at-1.24.57-PM.png” alt=”” width=”540″ height=”1055″ //a
pWe’re counting down to the final hours quick, so click stronga title=”Thrive Market Special” href=”http://thrv.me/sissongift” target=”_blank” rel=”nofollow”here/a/strong, order anything from Thrive Market, and you#8217;ll get all the free gifts above delivered directly to your inbox. Hurry, […]

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This post was originally published on this site

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You can learn a lot about a person based on their cereal preference. Someone who fills their bowl with Froot Loops is fundamentally different from a Frosted Flakes loyalist, just as the individual who happily slurps leftover chocolate milk from Cocoa Puffs might as well be on a different planet than the person who reaches for Raisin Bran.

So tell us: If you could only choose one favorite cereal, what would it be? It’s a hard question for sure, but it’s very important that you have an answer. Once you’ve decided, read on to see what that says about your personality.

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